Term Name: guanadrel
Synonyms: 1-(1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanidine, guanadrel, guanadrelum
Definition: A spiroketal resulting from the formal condensation of the keto group of cyclohexanone with the hydroxy groups of 1-(2,3-dihydroxypropyl)guanidine. A postganglionic adrenergic blocking agent formerly used (generally as the sulfate salt) for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching).
Ontology: ChEBI [CHEBI:5555]  ( EBI )

Relationships
is a type of: guanidines spiroketal
has_role: adrenergic antagonist antihypertensive agent
inverse is_conjugate_acid_of: guanadrel(1+)
is_conjugate_base_of: guanadrel(1+)