Term Name: serotonin uptake inhibitor
Synonyms: serotonin reuptake inhibitor, SSRI
Definition: A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
Ontology: ChEBI [CHEBI:50949]  ( EBI )

Relationships
is a type of: serotonergic drug
inverse has_role: (R)-fluoxetine (R)-fluoxetine hydrochloride (R,R)-tramadol (R,R)-tramadol hydrochloride (S)-fenfluramine (S)-fenfluramine hydrochloride (S)-fluoxetine (S)-fluoxetine hydrochloride (S,S)-tramadol (S,S)-tramadol hydrochloride amoxapine chlorphenamine citalopram citalopram hydrobromide clomipramine cocaine desipramine escitalopram hydrobromide fenfluramine fenfluramine hydrochloride fluoxetine fluoxetine hydrochloride fluvoxamine LY-367,265 methadone minaprine N-methylparoxetine nefazodone nefopam nefopam hydrochloride noribogaine olanzapine paroxetine paroxetine hydrochloride paroxetine maleate RTI-83 sertraline sertraline hydrochloride sibutramine tramadol tramadol hydrochloride trazodone trazodone hydrochloride venlafaxine vilazodone vilazodone hydrochloride