Term Name: vandetanib
Synonyms: 4-BROMO-2-FLUORO-N-[(4E)-6-METHOXY-7-[(1-METHYLPIPERIDIN-4-YL)METHOXY]QUINAZOLIN-4(1H)-YLIDENE]ANILINE, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine, vandetanib, Zactima, ZD 6474, ZD6474
Definition: A quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.
Ontology: ChEBI [CHEBI:49960]  ( EBI )

Relationships
is a type of: aromatic ether organobromine compound organofluorine compound piperidines quinazolines secondary amine
has_role: antineoplastic agent tyrosine kinase inhibitor
inverse has_functional_parent: linkable vandetanib analogue