Term Name: etacrynic acid
Synonyms: (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid, [2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid, acide etacrynique, acido etacrinico, acidum etacrynicum, Crinuryl, Edecril, Edecrina, Endecril, Etacrinic acid, etacrynic acid, Ethacrynate, ethacrynic acid, Hidromedin, Hydromedin, Methylenebutyrylphenoxyacetic acid, Mingit, Otacril, Reomax, Taladren, Uregit
Definition: An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Ontology: ChEBI [CHEBI:4876]  ( EBI )

Relationships
is a type of: aromatic ether aromatic ketone dichlorobenzene monocarboxylic acid
has_functional_parent: acetic acid
has_role: EC 2.5.1.18 (glutathione transferase) inhibitor ion transport inhibitor loop diuretic