Term Name: dimenhydrinate
Synonyms: (O-benzhydryl(dimethylamino)ethanol) 8-chlorotheophyllinate, 2-(diphenylmethoxy)-N,N-dimethylethanaminium 8-chloro-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide, 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), Benzhydryl-beta-dimethylaminoethylether 8-chlorotheophylline, beta-dimethylaminoethyl benzhydryl ether 1,3-dimethyl-8-chloroxanthine, dimenhidrinato, dimenhydrinate, dimenhydrinatum, diphenhydramine 8-chlorotheophyllinate, diphenhydramine 8-chlorotheophylline, diphenhydramine theoclate, N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate, O-benzhydryldimethylaminoethanol 8-chlorotheophyllinate
Definition: The diphenhydramine salt of 8-chlorotheophylline. Its effects are similar to those of diphenhydramine, but it is less potent. It was thought that by combining the antiemetic effects of diphenhydramine with the mild stimulant effects of 8-chlorotheophyline, the extreme drowsiness induced by the former would be mitigated. However, the sedation caused by diphenhydramine is considerably stronger than the stimulation caused by 8-chlorotheophylline. Dimenhydrinate is used mainly as an antiemetic in the prevention and treatment of motion sickness.
Ontology: ChEBI [CHEBI:4604]  ( EBI )

Relationships
is a type of: organic salt
has_part: 8-chlorotheophylline(1-) diphenhydramine
has_role: antiemetic H1-receptor antagonist