Term Name: carbidopa (anhydrous)
Synonyms: (-)-L-alpha-hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid, (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid, (alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid, (S)-(-)-carbidopa, (S)-carbidopa, carbidopum, L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid, L-alpha-methyldopahydrazine
Definition: 3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.
Ontology: ChEBI [CHEBI:39585]  ( EBI )

Relationships
is a type of: catechols hydrazines monocarboxylic acid
has_role: antiparkinson drug dopaminergic agent EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
inverse has_functional_parent: foscarbidopa
inverse has_part: carbidopa