Term Name: 3-methyl-2-oxovaleric acid
Synonyms: 2-Oxo-3-methyl-n-valeric acid, 2-Oxo-3-methylpentanoic acid, 2-Oxo-3-methylvalerate, 2-Oxo-3-methylvaleric acid, 2-Oxoisoleucine, 2-oxokolavenic acid, 3-ethyl-3-methylpyruvic acid, 3-methyl-2-oxopentanoic acid, 3-methyl-2-oxovaleric acid, alpha-keto-beta-methyl-n-valeric acid, alpha-keto-beta-methylvaleric acid, alpha-oxo-beta-methyl-n-valeric acid, alpha-oxo-beta-methylvaleric acid, ketoisoleucine
Definition: A 2-oxo monocarboxylic acid that is valeric acid carrying oxo- and methyl substituents at C-2 and C-3, respectively. An alpha-keto acid analogue and metabolite of isoleucine in man, animals and bacteria. Used as a clinical marker for maple syrup urine disease (MSUD).
Ontology: ChEBI [CHEBI:35932]  ( EBI )

Relationships
is a type of: 2-oxo monocarboxylic acid branched-chain keto acid
has subtype: (R)-3-methyl-2-oxovaleric acid (S)-3-methyl-2-oxovaleric acid
has_functional_parent: valeric acid
has_role: human metabolite
inverse is_conjugate_base_of: 3-methyl-2-oxovalerate
is_conjugate_acid_of: 3-methyl-2-oxovalerate