Term Name: paxilline
Synonyms: (+)-paxilline, (2R,4bS,6aS,12bS,12cR,14aS)-4b-hydroxy-2-(2-hydroxypropan-2-yl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-[1]benzopyrano[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one, (2R,4bS,6aS,12bS,12cR,14aS)-4b-hydroxy-2-(2-hydroxypropan-2-yl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one, paxiline, paxillin, paxilline
Definition: An indole diterpene alkaloid with formula C27H33NO4 isolated from Penicillium paxilli. It is a potent inhibitor of large conductance Ca2(+)- and voltage-activated K(+) (BK)-type channels.
Ontology: ChEBI [CHEBI:34907]  ( EBI )

Relationships
is a type of: diterpene alkaloid enone organic heterohexacyclic compound terpenoid indole alkaloid tertiary alcohol
has_role: anticonvulsant Aspergillus metabolite EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor genotoxin geroprotector mycotoxin Penicillium metabolite potassium channel blocker