Term Name: doxifluridine
Synonyms: 1-(beta-D-5-desoxyribofuranoxyl)-5-fluoruracil, 5'-deoxy-5-fluorouridine, 5'-DFUR, 5'-dFUrd, 5-fluoro-5'-deoxyuridine, doxifluridina, Doxifluridine, doxifluridinum, Furtulon, Ro 21-9738, Ro 219738
Definition: A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluorouracil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase.
Ontology: ChEBI [CHEBI:31521]  ( EBI )

Relationships
is a type of: organofluorine compound pyrimidine 5'-deoxyribonucleoside
has_role: antimetabolite antineoplastic agent prodrug