Term Name: DADLE
Synonyms: [D-Ala(2), D-Leu(5)]-enkephalin, [D-Ala(2), D-Leu(5)]enkephalin, [D-Ala(2),D-Leu(5)]enkephalin, [D-Ala2, D-Leu5]-enkephalin, BW 180C, BW-180C, BW180C, D-Ala(2),D-Leu(5)-enkephalin, D-Ala2, D-Leu5-enkephalin, enkephalin-(2-D-Ala, 5-D-Leu), H-Tyr-D-Ala-Gly-Phe-D-Leu-OH, H-Tyr-D-L-Ala-Gly-L-Phe-D-Leu-OH, L-tyrosyl-D-alanylglycyl-L-phenylalanyl-D-leucine, Tyr-D-Ala-Gly-Phe-D-Leu, Tyr-D-Ala-Gly-Phe-D-Leu-OH
Definition: A pentapeptide comprising of L-tyrosine, D-alanine, glycine, L-phenylalanine and D-leucine residues joined in sequence by peptide linkages. It is a synthetic delta-opioid agonist that induces hibernation, promotes survival of neurons and glial cells in the CNS, and exerts neuroprotection.
Ontology: ChEBI [CHEBI:234245]  ( EBI )

Relationships
is a type of: pentapeptide
has_role: antinociceptive agent autophagy inducer cardioprotective agent delta-opioid receptor agonist geroprotector mu-opioid receptor agonist neuroprotective agent opioid analgesic