Term Name: | DADLE |
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Synonyms: | [D-Ala(2), D-Leu(5)]-enkephalin, [D-Ala(2), D-Leu(5)]enkephalin, [D-Ala(2),D-Leu(5)]enkephalin, [D-Ala2, D-Leu5]-enkephalin, BW 180C, BW-180C, BW180C, D-Ala(2),D-Leu(5)-enkephalin, D-Ala2, D-Leu5-enkephalin, enkephalin-(2-D-Ala, 5-D-Leu), H-Tyr-D-Ala-Gly-Phe-D-Leu-OH, H-Tyr-D-L-Ala-Gly-L-Phe-D-Leu-OH, L-tyrosyl-D-alanylglycyl-L-phenylalanyl-D-leucine, Tyr-D-Ala-Gly-Phe-D-Leu, Tyr-D-Ala-Gly-Phe-D-Leu-OH |
Definition: | A pentapeptide comprising of L-tyrosine, D-alanine, glycine, L-phenylalanine and D-leucine residues joined in sequence by peptide linkages. It is a synthetic delta-opioid agonist that induces hibernation, promotes survival of neurons and glial cells in the CNS, and exerts neuroprotection. |
Ontology: | ChEBI [CHEBI:234245] ( EBI ) |