Term Name: | thiamet G |
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Synonyms: | (3aR,5R,6S,7R,7aR)-2-(ethylamino)-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, 2-(ethylamino)-3aR,6S,7R,7aR-tetrahydro-5R-(hydroxymethyl)-5H-pyrano[3,2-d]thiazole-6,7-diol, thiamet-G |
Definition: | A pyranothiazole that is (3aR,7aR)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole substituted by an ethylamino, hydroxymethyl, hydroxy, and hydroxy groups at positions 2, 5R, 6S, and 7R. It is a potent and selective inhibitor of O-GlcNAcase (Ki = 21 nM). |
Ontology: | ChEBI [CHEBI:233586] ( EBI ) |