Term Name: GSK046
Synonyms: 4-acetamido-3-fluoro-N-((1R,4S)-4-hydroxycyclohexyl)-5-((S)-1-phenylethoxy)benzamide, 4-acetamido-3-fluoro-N-(trans-4-hydroxycyclohexyl)-5-[(1S)-1-phenylethoxy]benzamide, 4-acetamido-3-fluoro-N-[(1r,4S)-4-hydroxycyclohexyl]-5-[(1S)-1-phenylethoxy]benzamide, GSK 046, GSK-046, iBET-BD2
Definition: A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-acetamido-3-fluoro-5-[(1S)-1-phenylethoxy]benzoic acid with the amino group of trans-4-aminocyclohexanol. It is a potent pan-BD2 bromodomain inhibitor.
Ontology: ChEBI [CHEBI:231669]  ( EBI )

Relationships
is a type of: acetamides aromatic ether benzamides benzenes cyclohexanols monofluorobenzenes secondary carboxamide
has_role: antineoplastic agent bromodomain-containing protein 4 inhibitor