Term Name: tasisulam
Synonyms: LY 573636, LY-573636, LY573636, N-(2,4-dichlorobenzoyl)-5-bromothiophene-2-sulfonamide, N-(5-bromothiophen-2-yl)sulfonyl-2,4-dichlorobenzamide, N-[(5-bromothiophen-2-yl)sulfonyl]-2,4-dichlorobenzamide, tasisulam, tasisulamum
Definition: A thiophene substituted by a 2,4-dichlorobenzamide-N-sulfonyl and bromo groups at positions 2 and 4, respectively. It induces tumour cell apoptosis via ROS induction and mitochondrial membrane potential loss and currently in clinical development for the treatment of cancer.
Ontology: ChEBI [CHEBI:231621]  ( EBI )

Relationships
is a type of: dichlorobenzene N-sulfonylcarboxamide organobromine compound thiophenes
has_role: angiogenesis inhibitor antineoplastic agent apoptosis inducer