Term Name: sotagliflozin
Synonyms: (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)- 6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol, (2S,3R,4R,5S,6R)-2-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-(methylsulfanyl)tetrahydro-2H-pyran-3,4,5-triol, (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(methylsulfanyl)oxane-3,4,5-triol, Inpefa, LP-802034, LX 4211, LX-4211, LX4211, methyl (5S)-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1-thio-beta-L-xylopyranoside, sotagliflozin, sotagliflozina, sotagliflozine, sotagliflozinum, Zynquista
Definition: An S-glycosyl compound that is 1-thio-beta-L-xylopyranose in which the anomeric hydroxy group is replaced by a 4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl group and the thiol is replaced by a methylsulfanediyl group. It is an inhibitor of SGLT1 and SGLT2 that is approved to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes mellitus, chronic kidney disease, and other cardiovascular risk.
Ontology: ChEBI [CHEBI:229226]  ( EBI )

Relationships
is a type of: aromatic ether C-glycosyl compound monochlorobenzenes S-glycosyl compound
has_role: antihypertensive agent cardioprotective agent hypoglycemic agent sodium-glucose transport protein subtype 1 inhibitor sodium-glucose transport protein subtype 2 inhibitor