Term Name: PYR-41
Synonyms: 4-[4-(5-nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester, ethyl 4-{4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl}benzoate, PYR 41, PYR41, UBEI-41
Definition: An ethyl ester resulting from the formal condensation of the carboxy group of 4-{4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl}benzoic acid with ethanol. It is an irreversible and cell-permeable inhibitor of ubiquitin-activating enzyme E1.
Ontology: ChEBI [CHEBI:192973]  ( EBI )

Relationships
is a type of: benzoate ester C-nitro compound ethyl ester furans pyrazolidines
has subtype: (E)-PYR-41 (Z)-PYR-41
has_role: antineoplastic agent EC 6.2.1.45 (E1 ubiquitin-activating enzyme) inhibitor