Term Name: LY 379268
Synonyms: (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, LY-379,268, LY-379268, LY379268
Definition: An organic heterobicyclic compound that is (1R,5S)-2-oxabicyclo[3.1.0]hexane carrying amino, carboxy, and carboxy groups at positions 4R, 4R and 6R, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 and mGluR3 (EC50 = 2.69 nM and 4.48 nM, respectively) that exhibits antipsychotic-like action in animal models of schizophrenia.
Ontology: ChEBI [CHEBI:192545]  ( EBI )

Relationships
is a type of: amino dicarboxylic acid bridged compound organic heterobicyclic compound
has_role: antipsychotic agent anxiolytic drug metabotropic glutamate receptor agonist neuroprotective agent