Term Name: PB28
Synonyms: 1-(3-(5-methoxytetralin-1-yl)propyl)-4-cyclohexylpiperazine, 1-cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine, 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl]piperazine, 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine, PB 28, PB-28
Definition: A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities.
Ontology: ChEBI [CHEBI:189648]  ( EBI )

Relationships
is a type of: aromatic ether piperazines tetralins
has_role: anticoronaviral agent antineoplastic agent apoptosis inducer sigma-2 receptor agonist