Term Name: ML162
Synonyms: 2-chloro-N-(3-chloro-4-methoxyphenyl)-N-{2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl}acetamide, DPI7, ML 162, ML-162, Molecular Libraries 162
Definition: A monochlorobenzene that is benzene substituted by (chloroacetyl){2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl}amino, chloro and methoxy groups at positions 1, 3 and 4, respectively. It is a covalent inhibitor of glutathione peroxidase 4 (GPX4) that induces ferroptosis in cells.
Ontology: ChEBI [CHEBI:176499]  ( EBI )

Relationships
is a type of: monochlorobenzenes monomethoxybenzene organochlorine compound secondary carboxamide tertiary carboxamide thiophenes
has_role: EC 1.11.1.9 (glutathione peroxidase) inhibitor ferroptosis inducer