Term Name: 5-aminolevulinic acid
Synonyms: 5-ALA, 5-Amino-4-oxopentanoate, 5-amino-4-oxopentanoic acid, 5-Amino-4-oxovaleric acid, 5-Aminolevulinate, aminolevulinic acid, dALA, delta-ALA, delta-aminolevulinic acid
Definition: The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Ontology: ChEBI [CHEBI:17549]  ( EBI )

Relationships
is a type of: 4-oxo monocarboxylic acid delta-amino acid
has_functional_parent: 4-oxopentanoic acid
has_role: antineoplastic agent dermatologic drug Escherichia coli metabolite human metabolite mouse metabolite photosensitizing agent plant metabolite prodrug Saccharomyces cerevisiae metabolite
inverse has_functional_parent: methyl 5-aminolevulinate
inverse is_conjugate_acid_of: 5-ammoniolevulinic acid
inverse is_conjugate_base_of: 5-aminolevulinate
inverse is_tautomer_of: 5-ammoniolevulinate
is_conjugate_acid_of: 5-aminolevulinate
is_conjugate_base_of: 5-ammoniolevulinic acid
is_tautomer_of: 5-ammoniolevulinate