Term Name: sapacitabine
Synonyms: 1-(2-cyano-2-deoxy-beta-D-arabinofuranosyl)-4-(hexadecanoylamino)pyrimidin-2(1H)-one, CS 682, CS-682, CS682, CYC 682, CYC-682, CYC682, N-(1-(2-cyano-2-deoxy-beta-D-arabinofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl)hexadecanamide, N-[1-(2-cyano-2-deoxy-beta-D-arabinofuranosyl)-2-oxo-1,2-dihydropyrimidine-4-yl]hexadecanamide, PCNDAC, sapacitabina, sapacitabine, sapacitabinum
Definition: A nucleoside analogue resulting from the formal condensation of the carboxy group of hexadecanoic acid with the amino group of CNDAC. It is the prodrug of CNDAC and is currently in clinical development for the treatment of acute myeloid leukemia (AML).
Ontology: ChEBI [CHEBI:145429]  ( EBI )

Relationships
is a type of: nitrile nucleoside analogue secondary carboxamide
has_functional_parent: CNDAC hexadecanoic acid
has_role: antimetabolite antineoplastic agent DNA synthesis inhibitor prodrug