| Synonyms: |
1-beta-D-Arabinofuranosyl-5-azacytosine,
4-amino-1-beta-D-arabinofuranosyl-1,3,5-triazin-2(1H)-one,
4-Amino-1-beta-D-arabinofuranosyl-s-triazin-2(1H)-one,
5-azacytarabine,
5-azacytosine arabinoside,
Ara-AC,
fazarabina,
fazarabine,
fazarabinum
|
| Definition: |
An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-arabinofuranosyl residue via an N-glycosidic linkage. A synthetic analogue of cytosine arabinoside and 5-azacytidine that incorporates structural features of both compounds, it shows good activity against a variety of transplanted tumors. |