Term Name: 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea
Synonyms: 1-(1-methyl-1H-indol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea, 3-(3-methyl-1,2-thiazol-5-yl)-1-(1-methylindol-5-yl)urea, N-(1-methyl-1H-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea, N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea, SB 204741, SB-204741, SB204741
Definition: A member of ther class of ureas that is urea in which a hydrogen attached to one of the nitrogens has been replaced by an N-methylindol-5-yl group, while a hydrogen attached to the other nitrogen has been replaced by a 3-methyl-1,2-thiazol-5-yl group. It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor.
Ontology: ChEBI [CHEBI:140936]  ( EBI )

Relationships
is a type of: 1,2-thiazoles indoles ureas
has_role: receptor modulator serotonergic antagonist