Term Name: GSK2656157
Synonyms: 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)-ethanone, 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methylpyridin-2-yl)ethanone, PERK inhibitor
Definition: A pyrrolopyrimidine that is 7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine which has been substituted at position 5 by a 4-fluoro-2,3-dihydro-1H-indol-5-yl group, the nitrogen of which has been acylated by a (6-methylpyridin-2-yl)acetyl group. An orally bioavailable PERK inhibitor.
Ontology: ChEBI [CHEBI:139047]  ( EBI )

Relationships
is a type of: biaryl indoles methylpyridines organofluorine compound pyrrolopyrimidine tertiary carboxamide
has_role: antineoplastic agent EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor PERK inhibitor