Term Name: bis(7)-tacrine
Synonyms: B7T, bis(7)-tetrahydroaminacrine, heptylene-bis(tacrine), N,N'-bis(1,2,3,4-tetrahydro-9-acridinyl)-1,7-heptanediamine, N,N'-di(1,2,3,4-tetrahydroacridin-9-yl)heptane-1,7-diamine
Definition: A secondary amino compound consisting of two molecules of tacrine that are linked together through their exocyclic amino groups by a heptane-1,7-diyl chain. Bis(7)-tacrine is an acetylcholinesterase (AChE)inhibitor (IC50 0.40 nM, >1,000 times more potent than tacrine). It has also been found to protect against H2O2 -induced apoptosis in rat pheochromocytoma cells.
Ontology: ChEBI [CHEBI:138435]  ( EBI )

Relationships
is a type of: secondary amino compound
has_functional_parent: tacrine
has_role: apoptosis inhibitor EC 1.14.13.39 (nitric oxide synthase) inhibitor EC 3.1.1.7 (acetylcholinesterase) inhibitor neuroprotective agent