Term Name: venetoclax
Synonyms: 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-(3-nitro-4-{[(oxan-4-yl)methyl]amino}benzene-1-sulfonyl)-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide, ABT 199, ABT-199, ABT199, GDC 0199, Venclexta, venetoclax
Definition: A member of the class of pyrrolopyridines that is a potent inhibitor of the antiapoptotic protein B-cell lymphoma 2. It is used for treamtment of chronic lymphocytic leukemia with 17p deletion.
Ontology: ChEBI [CHEBI:133021]  ( EBI )

Relationships
is a type of: aromatic ether C-nitro compound monochlorobenzenes N-alkylpiperazine N-arylpiperazine N-sulfonylcarboxamide oxanes pyrrolopyridine
has_role: antineoplastic agent apoptosis inducer B-cell lymphoma 2 inhibitor