Term Name: PHA-533533
Synonyms: (2S)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxopyrrolidin-1-yl)phenyl]propanamide, PHA 533533, PHA533533
Definition: A carboxamide resulting from the formal condensation of the primary amino group of 5-cyclopropyl-1H-pyrazol-3-amine with the carboxy group of (2S)-2-phenylpropanoic acid in which the phenyl ring is substituted at the para position by a 2-oxopyrrolidin-1-yl group. A CDK2 inhibitor with antineoplastic activity.
Ontology: ChEBI [CHEBI:132239]  ( EBI )

Relationships
is a type of: cyclopropanes pyrazoles pyrrolidin-2-ones secondary carboxamide tertiary carboxamide
has_role: antineoplastic agent EC 2.7.11.22 (cyclin-dependent kinase) inhibitor