Term Name: zileuton
Synonyms: (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea, 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea, Leutrol, N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea, N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea, zileuton, zileutonum, Zyflo
Definition: A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma.
Ontology: ChEBI [CHEBI:10112]  ( EBI )

Relationships
is a type of: 1-benzothiophenes ureas
has_parent_hydride: 1-benzothiophene
has_role: anti-asthmatic drug EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor ferroptosis inhibitor leukotriene antagonist non-steroidal anti-inflammatory drug