- Title
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Endothelin neurotransmitter signalling controls zebrafish social behaviour
- Authors
- Carreño Gutiérrez, H., Colanesi, S., Cooper, B., Reichmann, F., Young, A.M.J., Kelsh, R.N., Norton, W.H.J.
- Source
- Full text @ Sci. Rep.
ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. PHENOTYPE:
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ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. PHENOTYPE:
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ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. PHENOTYPE:
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ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. PHENOTYPE:
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Expression of ednraa in the adult zebrafish brain. (a–e) In situ hybridisation showing ednraa gene expression in the ventral zone of the ventral telencephalon (Vv), the preoptic area (POA), dorsal thalamus (DT), periaqueductal grey (PGZ), ventral hypothalamus (Hv) and periventricular nucleus of the hypothalamus (PVN).
EXPRESSION / LABELING:
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Altered distribution of arginine vasopressin neurons in ednraa−/−. In situ hybridisation showing that expression of arginine vasopressin (avp) is similar in the brain of WT (a,c,e) and ednraa−/− (b,d,f) at 6 days (a,b) and 12 days (c,d). (e,f) Reduced expression of avp in the ventral parvocellular preoptic area of ednraa−/− of adult fish. (g,h) In situ hybridisation showing that oxytocin (oxt) expression is similar in WT and ednraa−/− adult fish. (i,j) Anti-AVP antibody staining shows reduced labelling in the parvocellular preoptic area of ednraa−/− (j) compared to WT (i) (arrowheads). Dorsal magnocellular neurons have a larger cell body and thicker projections. (k) Reduced levels of AVP in the brain of ednraa−/− compared to WT. (l) Decreased whole-body cortisol levels in ednraa−/− compared to WT. *p < 0.05, ***p < 0.001.
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ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. |
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ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. |
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ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions. PHENOTYPE:
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