FIGURE SUMMARY
Title

Neural stem cells induce the formation of their physical niche during organogenesis

Authors
Seleit, A., Krämer, I., Riebesehl, B.F., Ambrosio, E.M., Stolper, J.S., Lischik, C.Q., Dross, N., Centanin, L.
Source
Full text @ Elife

Conservation of nBCs in neuromasts of other teleost fish.

(A) DAPI-stained neuromast Peocilia formosa, a close relative of medaka, reveals the presence of nBCs as assessed by their distinct morphology and relative location (N = 10 neuromasts in a single 1 month old fish). (B) Close-up on a Peocilia formosa neuromast reveals that nBCs are immediately adjacent to mantle cells (N = 10 border cells in four neuromasts). (C) DAPI-stained neuromast of Danio rerio, a distant relative of medaka, reveals the presence of nBCs as assessed by their distinct morphology and location (N=>5 neuromasts in three larvae). (D) Close-up of a zebrafish neuromast reveals that nBCs intimately associate with mantle cells (N=>5 neuromasts in three larvae). (E) Tg(ol.K15::H2B-eGFP) shows labelling of the skin epithelium and mantle cells in a 5 dph zebrafish larvae. (F) Close-up of a Tg(ol.K15::H2B-eGFP) zebrafish neuromast shows labelling of cells within the neural lineage and nBCs (N= 5 neuromasts in three larvae). Scalebars = 10 µm, except in panel E, Scalebar = 100 µm.

Acknowledgments
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