ZFIN All Figures, Sasaki <i>et al.</i>, 2017

Fig. 1

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	EGFP
Fish:	zf155Tg zf155Tg + MO3-atp6v0ca spns1^{hi891Tg/hi891Tg}; zf155Tg spns1^{hi891Tg/hi891Tg}; zf155Tg + MO3-atp6v0ca
Knockdown Reagent:	MO3-atp6v0ca
Anatomical Term:	cell autophagosome
Stage:	Protruding-mouth

Expression / Labeling details

PHENOTYPE:

Fish:	spns1^{hi891Tg/hi891Tg} WT + MO1-spns1 zf155Tg + MO3-atp6v0ca spns1^{hi891Tg/hi891Tg}; zf155Tg spns1^{hi891Tg/hi891Tg} + MO1-atp6v0ca WT + MO1-atp6v0ca + MO1-spns1 spns1^{hi891Tg/hi891Tg}; zf155Tg + MO3-atp6v0ca
Knockdown Reagents:	MO1-atp6v0ca MO1-spns1 MO3-atp6v0ca
Observed In:	cell autolysosome cell autophagosome cell lysosome whole organism
Stage Range:	Long-pec to Day 6

Phenotype details

Fig. 2

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	atp6v0ca^{hi1207Tg/hi1207Tg} spns1^{hi891Tg/hi891Tg} WT + MO1-spns1 atp6v0ca^{hi1207Tg/hi1207Tg} + MO1-spns1 spns1^{hi891Tg/hi891Tg} + MO1-atp6v0ca
Knockdown Reagents:	MO1-atp6v0ca MO1-spns1
Observed In:	whole organism yolk
Stage Range:	Long-pec to Days 7-13

Phenotype details

Fig. 3

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	EGFP mCherry
Antibody:	Ab4-map1lc3
Fish:	atp6v0ca^{hi1207Tg/hi1207Tg} spns1^{hi891Tg/hi891Tg} zf155Tg; zf3133Tg atp6v0ca^{hi1207Tg/hi1207Tg}; zf155Tg; zf3133Tg spns1^{hi891Tg/hi891Tg}; zf155Tg; zf3133Tg
Anatomical Terms:	cell autolysosome cell autophagosome cell lysosome cell phagophore
Stage:	Protruding-mouth

Expression / Labeling details

PHENOTYPE:

Fish:	atp6v0ca^{hi1207Tg/hi1207Tg} spns1^{hi891Tg/hi891Tg} atp6v0ca^hi1207Tg; zf155Tg spns1^{hi891Tg/hi891Tg}; zf155Tg atp6v0ca^{hi1207Tg/hi1207Tg}; zf155Tg; zf3133Tg spns1^{hi891Tg/hi891Tg}; zf155Tg; zf3133Tg
Observed In:	cell autolysosome cell autophagosome cell lysosome cell phagophore
Stage:	Protruding-mouth

Phenotype details

Fig. 4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	spns1^{hi891Tg/hi891Tg}; zf155Tg spns1^{hi891Tg/hi891Tg}; zf155Tg; zf3133Tg
Observed In:	whole organism yolk
Stage Range:	Long-pec to Day 6

Phenotype details

Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	atp6v0ca^{zf3063/zf3063}; zf155Tg spns1^{hi891Tg/hi891Tg}; zf155Tg atp6v0ca^{zf3063/zf3063}; spns1^{hi891Tg/hi891Tg}; zf155Tg
Observed In:	cell autolysosome cell autophagosome
Stage:	Protruding-mouth

Phenotype details

Fig. 6

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	glb1 rgn serpine1
Fish:	atp6v0ca^{zf3063/zf3063}; zf155Tg spns1^{hi891Tg/hi891Tg}; zf155Tg atp6v0ca^{zf3063/zf3063}; spns1^{hi891Tg/hi891Tg}; zf155Tg
Anatomical Term:	whole organism
Stage:	Protruding-mouth

Expression / Labeling details

PHENOTYPE:

Fish:	atp6v0ca^{zf3063/zf3063}; zf155Tg spns1^{hi891Tg/hi891Tg}; zf155Tg atp6v0ca^{zf3063/zf3063}; spns1^{hi891Tg/hi891Tg}; zf155Tg
Observed In:	whole organism
Stage:	Protruding-mouth

Phenotype details

Fig. 7

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	spns1^{hi891Tg/hi891Tg} spns1^{hi891Tg/hi891Tg} + MO1-atp6v0ca atp6v0ca^{zf3063/zf3063}; spns1^{hi891Tg/hi891Tg}; zf155Tg atp6v0ca^{zf3063/zf3063}; spns1^{hi891Tg/hi891Tg}; zf155Tg + MO1-atp6v0ca
Knockdown Reagent:	MO1-atp6v0ca
Observed In:	whole organism
Stage Range:	Long-pec to Days 7-13

Phenotype details

Acknowledgments

Full text @ Autophagy

Sasaki et al., 2017

ZDB-PUB-161123-2
PMID:27875093

Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase

Sasaki et al., 2017 ZDB-PUB-161123-2 PMID:27875093

Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase

Sasaki et al., 2017

ZDB-PUB-161123-2
PMID:27875093