ZFIN ID: ZDB-EXP-211109-1
Experiment Conditions Description: chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F
chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F
Name: chemical treatment by environment
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: Z-Val-Ala-Asp(OMe)-CH2F
Synonyms: N-[(benzyloxy)carbonyl]-L-valyl-N-[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]-L-alaninamide, pan-caspase inhibitor, Z-L-Val-L-Ala-L-Asp(OMe)-CH2F, Z-VAD(OMe)-FMK, Z-VAD-FMK, Z-Val-Ala-Asp(OMe)-fluoromethyl ketone, Z-Val-Ala-Asp(OMe)-FMK
Definition: A tripeptide consisting of Z-Val-Ala-Asp(OMe) in which the C-terminal OH group has been replaced by a fluoromethyl group. An irreversible pan-caspase inhibitor.
Ontology: Chebi [CHEBI:137045]
Publication: Gregory-Evans et al., 2011