ZFIN ID: ZDB-EXP-210203-1
Experiment Conditions Description: chemical treatment: RF9
chemical treatment: RF9
Name: chemical treatment
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: RF9
Synonyms: 1-adamantanecarbonyl-Arg-Phe-NH2, N(2)-(tricyclo[,7)]decan-1-ylcarbonyl)-L-arginyl-L-phenylalaninamide, neuropeptide FF receptor antagonist, NPFF receptor antagonist, RF 9, RF-9
Definition: A dipeptide formed from L-arginine and L-phenylalaninamide residues in which a hydrogen attached to the nitrogen of the alpha-amino group of the arginine residue has been replaced by a 1-adamantanecarbonyl group. It has been reported to be a potent and selective antagonist of neuropeptide FF (NPFF) receptors, but more recently found to be an agonist at both NPFF1R and the kisspeptin receptor (KISS1R).
Ontology: Chebi [CHEBI:140980]
Publication: Lee et al., 2019