| ZFIN ID: ZDB-EXP-210203-1 |
Experiment Conditions Description: chemical treatment: RF9
| chemical treatment: RF9 |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | RF9 |
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| Synonyms: | 1-adamantanecarbonyl-Arg-Phe-NH2, N(2)-(tricyclo[3.3.1.1(3,7)]decan-1-ylcarbonyl)-L-arginyl-L-phenylalaninamide, neuropeptide FF receptor antagonist, NPFF receptor antagonist, RF 9, RF-9 |
| Definition: | A dipeptide formed from L-arginine and L-phenylalaninamide residues in which a hydrogen attached to the nitrogen of the alpha-amino group of the arginine residue has been replaced by a 1-adamantanecarbonyl group. It has been reported to be a potent and selective antagonist of neuropeptide FF (NPFF) receptors, but more recently found to be an agonist at both NPFF1R and the kisspeptin receptor (KISS1R). |
| Ontology: | ChEBI [CHEBI:140980] ( EBI ) |
| Publication: | Lee et al., 2019 |
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