ZFIN ID: ZDB-EXP-170512-2
Experiment Conditions Description: chemical treatment: Z-Val-Ala-Asp(OMe)-CH2F
chemical treatment: Z-Val-Ala-Asp(OMe)-CH2F
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: Z-Val-Ala-Asp(OMe)-CH2F
Synonyms: N-[(benzyloxy)carbonyl]-L-valyl-N-[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]-L-alaninamide, pan-caspase inhibitor, Z-L-Val-L-Ala-L-Asp(OMe)-CH2F, Z-VAD(OMe)-FMK, Z-VAD-FMK, Z-Val-Ala-Asp(OMe)-fluoromethyl ketone, Z-Val-Ala-Asp(OMe)-FMK
Definition: A tripeptide consisting of Z-Val-Ala-Asp(OMe) in which the C-terminal OH group has been replaced by a fluoromethyl group. An irreversible pan-caspase inhibitor.
Ontology: ChEBI [CHEBI:137045]  ( EBI )
Publication: Casano et al., 2016