| ZFIN ID: ZDB-EXP-170105-4 |
Experiment Conditions Description: chemical treatment: tofacitinib
| chemical treatment: tofacitinib |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | tofacitinib |
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| Synonyms: | 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, CP 690550, CP-690550, Tasocitinib, tofacitinib, tofacitinibum |
| Definition: | A pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis. |
| Ontology: | ChEBI [CHEBI:71200] ( EBI ) |
| Publication: | Sertori et al., 2016 |
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