PUBLICATION
A zebrafish homologue of the murine Hox-2.1 gene
- Authors
- Njolstad, P.R., Molven, A., and Fjose, A.
- ID
- ZDB-PUB-961014-837
- Date
- 1988
- Source
- FEBS letters 230: 25-30 (Journal)
- Registered Authors
- Fjose, Anders, Molven, Anders
- Keywords
- none
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Bacteriophage lambda/genetics
- Base Sequence
- Cyprinidae/genetics*
- DNA/genetics
- DNA, Recombinant
- Drosophila melanogaster/genetics
- Gene Expression Regulation
- Genes, Homeobox*
- Mice
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Sequence Homology, Nucleic Acid
- Transcription, Genetic
- Zebrafish/embryology
- Zebrafish/genetics*
- PubMed
- 2895022 Full text @ FEBS Lett.
Citation
Njolstad, P.R., Molven, A., and Fjose, A. (1988) A zebrafish homologue of the murine Hox-2.1 gene. FEBS letters. 230:25-30.
Abstract
Homeobox-containing sequences were isolated from a genomic library of zebrafish (Brachydanio rerio). A lambda clone containing two homeobox cross-hybridizing regions was characterized. DNA sequencing of one of these regions (ZF-21) revealed that it contains a homeobox closely related to the Antennapedia class of Drosophila homeobox sequences. Moreover, the deduced amino acid sequence of the C-terminal end (81 residues including the homeobox) is identical to the corresponding part of the murine Hox-2.1 protein. Similar to Hox-2.1, a ZF-21 derived transcript of 2.3 kb is present in embryos at the somite forming stages.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping