PUBLICATION

A zebrafish homologue of the murine Hox-2.1 gene

Authors
Njolstad, P.R., Molven, A., and Fjose, A.
ID
ZDB-PUB-961014-837
Date
1988
Source
FEBS letters   230: 25-30 (Journal)
Registered Authors
Fjose, Anders, Molven, Anders
Keywords
none
MeSH Terms
  • Amino Acid Sequence
  • Animals
  • Bacteriophage lambda/genetics
  • Base Sequence
  • Cyprinidae/genetics*
  • DNA/genetics
  • DNA, Recombinant
  • Drosophila melanogaster/genetics
  • Gene Expression Regulation
  • Genes, Homeobox*
  • Mice
  • Molecular Sequence Data
  • Nucleic Acid Hybridization
  • Sequence Homology, Nucleic Acid
  • Transcription, Genetic
  • Zebrafish/embryology
  • Zebrafish/genetics*
PubMed
2895022 Full text @ FEBS Lett.
Abstract
Homeobox-containing sequences were isolated from a genomic library of zebrafish (Brachydanio rerio). A lambda clone containing two homeobox cross-hybridizing regions was characterized. DNA sequencing of one of these regions (ZF-21) revealed that it contains a homeobox closely related to the Antennapedia class of Drosophila homeobox sequences. Moreover, the deduced amino acid sequence of the C-terminal end (81 residues including the homeobox) is identical to the corresponding part of the murine Hox-2.1 protein. Similar to Hox-2.1, a ZF-21 derived transcript of 2.3 kb is present in embryos at the somite forming stages.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping