PUBLICATION

Radiosensitivity and time of origin of Mauthner neuron in the zebra fish

Authors
Kimmel, C.B., Sessions, S.K., and Kimmel, R.J.
ID
ZDB-PUB-961014-597
Date
1978
Source
Developmental Biology   62(2): 526-529 (Journal)
Registered Authors
Kimmel, Charles B., Kimmel, Reida J.
Keywords
none
MeSH Terms
  • Animals
  • Cell Cycle
  • Dose-Response Relationship, Radiation
  • Fertilization
  • Fishes/embryology*
  • Gamma Rays
  • Neurons/radiation effects*
  • Time Factors
PubMed
627315 Full text @ Dev. Biol.
Abstract
Mauthner (M-) cells were frequently missing in zebra fishes γ-irradiated with 1000 rad during gastrula stages until about 12 hr after fertilization. The cells were resistant after this time. The S phase of the final cell cycle of M-cell precursors ends between 9 and 12 hr. This indicates that the M-cell precursors are sensitive to irradiation before the end of their final cell division. The M-cell deletions appear to be at random and require killing of only one or a small number of cells.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping