PUBLICATION

Recent insights into zebrafish cardiac regeneration

Authors
Sanz-Morejón, A., Mercader, N.
ID
ZDB-PUB-200701-10
Date
2020
Source
Current opinion in genetics & development   64: 37-43 (Review)
Registered Authors
Mercader Huber, Nadia
Keywords
none
MeSH Terms
  • Animals
  • Heart/embryology
  • Heart/physiology*
  • Myocytes, Cardiac/cytology*
  • Regeneration*
  • Zebrafish/embryology
  • Zebrafish/physiology*
PubMed
32599303 Full text @ Curr. Opin. Genet. Dev.
Abstract
In humans, myocardial infarction results in ventricular remodeling, progressing ultimately to cardiac failure, one of the leading causes of death worldwide. In contrast to the adult mammalian heart, the zebrafish model organism has a remarkable regenerative capacity, offering the possibility to research the bases of natural regeneration. Here, we summarize recent insights into the cellular and molecular mechanisms that govern cardiac regeneration in the zebrafish.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping