PUBLICATION

Stay hydrated: basolateral fluids shaping tissues

Authors
Schliffka, M.F., Maître, J.L.
ID
ZDB-PUB-190826-21
Date
2019
Source
Current opinion in genetics & development   57: 70-77 (Other)
Registered Authors
Maître, Jean-Léon
Keywords
none
MeSH Terms
  • Animals
  • Body Water/cytology
  • Body Water/metabolism
  • Embryonic Development/genetics*
  • Extracellular Fluid/cytology
  • Extracellular Fluid/metabolism*
  • Mice
  • Morphogenesis/genetics*
  • Zebrafish/genetics
  • Zebrafish/growth & development
PubMed
31445440 Full text @ Curr. Opin. Genet. Dev.
Abstract
During development, embryos perform a mesmerizing choreography, which is crucial for the correct shaping, positioning and function of all organs. The cellular properties powering animal morphogenesis have been the focus of much attention. In contrast, much less consideration has been given to the invisible engine constituted by the intercellular fluid. Cells are immersed in fluid, of which the composition and physical properties have a considerable impact on development. In this review, we revisit recent studies from the perspective of the fluid, focusing on basolateral fluid compartments and taking the early mouse and zebrafish embryos as models. These examples illustrate how the hydration levels of tissues are spatio-temporally controlled and influence embryonic development.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping