PUBLICATION

Resident Macrophage Lookalikes of Unexpected Origin

Authors
Levraud, J.P., Herbomel, P.
ID
ZDB-PUB-190522-7
Date
2019
Source
Developmental Cell   49: 501-502 (Other)
Registered Authors
Herbomel, Philippe, Levraud, Jean-Pierre
Keywords
none
MeSH Terms
  • Animals
  • Ectoderm
  • Epidermis
  • Langerhans Cells*
  • Macrophages
  • Zebrafish*
PubMed
31112695 Full text @ Dev. Cell
Abstract
In this issue of Developmental Cell, Lin et al. (2019) identify in zebrafish skin macrophage-like cells that sample the environment through transepithelial protrusions and import antigen from the water for traditional tissue-resident macrophages. Remarkably, these "metaphocytes" originate from the epidermis, challenging current assumptions about the lineage of tissue-resident macrophages.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping