PUBLICATION

Zebrafish: A Premier Vertebrate Model for Biomedical Research in Indian Scenario

Authors
Sarasamma, S., Varikkodan, M.M., Liang, S.T., Lin, Y.C., Wang, W.P., Hsiao, C.D.
ID
ZDB-PUB-171013-7
Date
2017
Source
Zebrafish   14(6): 589-605 (Review)
Registered Authors
Hsiao, Chung-Der
Keywords
biomedical research, genetic disease, research in India, vertebrate model, zebrafish
MeSH Terms
  • Animals
  • Biomedical Research*
  • Disease Models, Animal*
  • Genomics/methods*
  • Humans
  • India
  • Zebrafish/embryology
  • Zebrafish/genetics*
PubMed
29023224 Full text @ Zebrafish
Abstract
The zebrafish (Danio rerio) is a versatile model organism that has been used in biomedical research for several decades to study a wide range of biological phenomena. There are many technical advantages of using zebrafish over other vertebrate models. They are readily available, hardy, easy, and inexpensive to maintain in the laboratory, have a short life cycle, and have excellent fecundity. Due to its optical clarity and reproducible capabilities, it has become one of the predominant models of human genetic diseases. Zebrafish research has made rapid strides in the United States and Europe, but in India the field is at an early stage and many researchers still remain unaware of the full research potential of this tiny fish. The zebrafish model system was introduced into India in the early 2000s. Up to now, more than 200 scientific referred articles have been published by Indian researchers. This review gives an overview of the current state of knowledge for zebrafish research in India, with the aim of promoting wider utilization of zebrafish for high level biological studies.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping