PUBLICATION
From neuron to behavior: Sensory-motor coordination of zebrafish turning behavior
- Authors
- Umeda, K., Shoji, W.
- ID
- ZDB-PUB-170323-12
- Date
- 2017
- Source
- Development, growth & differentiation 59(3): 107-114 (Review)
- Registered Authors
- Shoji, Wataru
- Keywords
- Channelrhodopsin, Rohon-Beard neuron, escape behavior, optogenetics, zebrafish
- MeSH Terms
-
- Animals
- Larva/cytology
- Larva/physiology
- Mechanotransduction, Cellular/physiology
- Neurons/cytology
- Neurons/physiology
- Optogenetics/methods
- Zebrafish/physiology*
- PubMed
- 28326550 Full text @ Dev. Growth Diff.
Citation
Umeda, K., Shoji, W. (2017) From neuron to behavior: Sensory-motor coordination of zebrafish turning behavior. Development, growth & differentiation. 59(3):107-114.
Abstract
Recent development of optogenetics brought non-invasive neural activation in living organisms. Transparent zebrafish larva is one of the suitable animal models for this technique, which enables us to investigate neural circuits for behaviors based on a whole individual nervous system. In this article we review our recent finding that suggests sensory-motor coordination in larval zebrafish escape behavior. When water vibration stimulates mechanosensory Rohon-Beard (RB) neurons, intra-spinal reflex circuit launches contralateral trunk muscle contraction that makes rapid body curvature for turning. In addition, positional information of the stimulus is conveyed to supra-spinal circuits, and then regulates the curvature strength for appropriate escape pathway from the threat. Sensory-motor coordination is a fundamental feature to adapt behaviors to environment, and zebrafish larvae would be an excellent model for elucidating its neural backbones.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping