PUBLICATION
New frontiers for zebrafish management
- Authors
- Lawrence, C.
- ID
- ZDB-PUB-160725-12
- Date
- 2016
- Source
- Methods in cell biology 135: 483-508 (Chapter)
- Registered Authors
- Lawrence, Christian
- Keywords
- Defined environment, Disease, Husbandry, Management, Nutrition, Zebrafish
- MeSH Terms
-
- Animals
- Aquaculture/methods
- Developmental Biology/methods*
- Laboratory Animal Science/methods*
- Models, Animal
- Zebrafish/genetics
- Zebrafish/growth & development*
- PubMed
- 27443941 Full text @ Meth. Cell. Biol.
Citation
Lawrence, C. (2016) New frontiers for zebrafish management. Methods in cell biology. 135:483-508.
Abstract
The zebrafish (Danio rerio) is a preeminent model organism with a wide and expanding utility for numerous scientific disciplines. The same features that once endeared this small freshwater minnow to developmental biologists combined with its relatively high genetic similarity to mammals and the advent of new, more efficient methods for genome editingĀ are now helping to spur expanded growth in its usage in various fields, including toxicology, drug discovery, transplant biology, disease modeling, and even aquaculture. Continued maturation and adoption of the zebrafish model system in these and other fields of science will require that methods and approaches for husbandry and management of these fish in controlled settings be refined and improved to the extent that, ultimately, zebrafish research becomes more reproducible, defined, cost-effective, and accessible to the masses. Knowledge and technology transfer from laboratory animal science and commercial aquaculture will be a necessary part of this development.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping