PUBLICATION

Next generation mothers: Maternal control of germline development in zebrafish

Authors
Dosch, R.
ID
ZDB-PUB-141123-5
Date
2015
Source
Critical reviews in biochemistry and molecular biology   50(1): 54-68 (Review)
Registered Authors
Dosch, Roland
Keywords
Early embryogenesis, gamete, genetics, germ cell, germ plasm, maternal-effect, oocyte, oogenesis
MeSH Terms
  • Animals
  • Embryo, Nonmammalian
  • Female
  • Gene Expression Regulation, Developmental*
  • Male
  • Mothers
  • Oocytes/physiology*
  • Oogenesis
  • Zebrafish/embryology*
  • Zebrafish/genetics
  • Zebrafish/growth & development
PubMed
25413788 Full text @ Crit. Rev. Biochem. Mol. Biol.
Abstract
Abstract In many animals, factors deposited by the mother into the egg control the earliest events in development of the zygote. These maternal RNAs and proteins play critical roles in oocyte development and the earliest steps of embryogenesis such as fertilization, cell division and embryonic patterning. Here, this article summarizes recent discoveries made on the maternal control of germline specification in zebrafish. Moreover, this review will discuss the major gaps remaining in our understanding of this process and highlight recent technical innovations in zebrafish, which allow tackling some of these questions in the near future.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping