PUBLICATION

In Vitro and in Vivo Fluorescent Imaging of a Monofunctional Chelated Platinum Complex Excitable Using Visible Light

Authors
Wu, S., Zhu, C., Zhang, C., Yu, Z., He, W., He, Y., Li, Y., Wang, J., and Guo, Z.
ID
ZDB-PUB-111114-15
Date
2011
Source
Inorganic chemistry   50(23): 11847-9 (Journal)
Registered Authors
Wang, Jing
Keywords
none
MeSH Terms
  • Animals
  • Antineoplastic Agents/chemistry*
  • Antineoplastic Agents/metabolism*
  • Cell Line, Tumor
  • Chelating Agents/chemistry*
  • Humans
  • Larva/metabolism
  • Light*
  • Molecular Imaging/methods*
  • Organoplatinum Compounds/chemistry*
  • Organoplatinum Compounds/metabolism*
  • Oxadiazoles/chemistry
  • Spectrometry, Fluorescence
  • Zebrafish
PubMed
22035018 Full text @ Inorg. Chem.
Abstract

The biological fluorescent distribution of a model antitumor monofunctional platinum(II) complex bearing a 7-nitro-2,1,3-benzoxadiazole fluorophore can be visualized in breast carcinoma MCF-7 cells, pulmonary carcinoma A549 cells, kidney epithelial 293T cells, and zebrafish larva.

Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping