PUBLICATION
In Vitro and in Vivo Fluorescent Imaging of a Monofunctional Chelated Platinum Complex Excitable Using Visible Light
- Authors
- Wu, S., Zhu, C., Zhang, C., Yu, Z., He, W., He, Y., Li, Y., Wang, J., and Guo, Z.
- ID
- ZDB-PUB-111114-15
- Date
- 2011
- Source
- Inorganic chemistry 50(23): 11847-9 (Journal)
- Registered Authors
- Wang, Jing
- Keywords
- none
- MeSH Terms
-
- Animals
- Antineoplastic Agents/chemistry*
- Antineoplastic Agents/metabolism*
- Cell Line, Tumor
- Chelating Agents/chemistry*
- Humans
- Larva/metabolism
- Light*
- Molecular Imaging/methods*
- Organoplatinum Compounds/chemistry*
- Organoplatinum Compounds/metabolism*
- Oxadiazoles/chemistry
- Spectrometry, Fluorescence
- Zebrafish
- PubMed
- 22035018 Full text @ Inorg. Chem.
Citation
Wu, S., Zhu, C., Zhang, C., Yu, Z., He, W., He, Y., Li, Y., Wang, J., and Guo, Z. (2011) In Vitro and in Vivo Fluorescent Imaging of a Monofunctional Chelated Platinum Complex Excitable Using Visible Light. Inorganic chemistry. 50(23):11847-9.
Abstract
The biological fluorescent distribution of a model antitumor monofunctional platinum(II) complex bearing a 7-nitro-2,1,3-benzoxadiazole fluorophore can be visualized in breast carcinoma MCF-7 cells, pulmonary carcinoma A549 cells, kidney epithelial 293T cells, and zebrafish larva.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping