PUBLICATION

Time-lapse imaging of neural development: Zebrafish lead the way into the fourth dimension

Authors
Rieger, S., Wang, F., and Sagasti, A.
ID
ZDB-PUB-110214-26
Date
2011
Source
Genesis (New York, N.Y. : 2000)   49(7): 534-45 (Review)
Registered Authors
Sagasti, Alvaro, Wang, Fang
Keywords
zebrafish, imaging, time-lapse, neural development, neurons
MeSH Terms
  • Animals
  • Developmental Biology*/instrumentation
  • Developmental Biology*/methods
  • Microscopy, Confocal
  • Molecular Imaging
  • Neurobiology*/instrumentation
  • Neurobiology*/methods
  • Neurogenesis/physiology*
  • Time-Lapse Imaging*/trends
  • Zebrafish/embryology
PubMed
21305690 Full text @ Genesis
Abstract
Time-lapse imaging is often the only way to appreciate fully the many dynamic cell movements critical to neural development. Zebrafish possess many advantages that make them the best vertebrate model organism for live imaging of dynamic development events. This review will discuss technical considerations of time-lapse imaging experiments in zebrafish, describe selected examples of imaging studies in zebrafish that revealed new features or principles of neural development, and consider the promise and challenges of future time-lapse studies of neural development in zebrafish embryos and adults.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping