PUBLICATION

Vertebrate maternal-effect genes: Insights into fertilization, early cleavage divisions, and germ cell determinant localization from studies in the zebrafish

Authors
Lindeman, R.E., and Pelegri, F.
ID
ZDB-PUB-091120-49
Date
2010
Source
Molecular reproduction and development   77(4): 299-313 (Review)
Registered Authors
Pelegri, Francisco
Keywords
none
MeSH Terms
  • Animals
  • Cell Cycle/physiology
  • Centrosome/metabolism
  • Chromosome Segregation
  • Cytoskeleton/metabolism
  • Embryo, Nonmammalian*/cytology
  • Embryo, Nonmammalian*/physiology
  • Embryonic Development/physiology*
  • Fertilization/physiology*
  • Gene Expression Regulation, Developmental*
  • Germ Cells*/cytology
  • Germ Cells*/physiology
  • Humans
  • Zebrafish/embryology*
  • Zebrafish/genetics*
  • Zebrafish/physiology
  • Zebrafish Proteins/genetics
  • Zebrafish Proteins/metabolism
PubMed
19908256 Full text @ Mol. Reprod. Dev.
Abstract
In the earliest stages of animal development prior to the commencement of zygotic transcription, all critical cellular processes are carried out by maternally-provided molecular products accumulated in the egg during oogenesis. Disruption of these maternal products can lead to defective embryogenesis. In this review, we focus on maternal genes with roles in the fundamental processes of fertilization, cell division, centrosome regulation, and germ cell development with emphasis on findings from the zebrafish, as this is a unique and valuable model system for vertebrate reproduction.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping