PUBLICATION

Transcriptome study in China

Authors
Han, Z.G., Zhao, G.P., and Chen, Z.
ID
ZDB-PUB-090210-8
Date
2003
Source
Comptes rendus biologies   326(10-11): 949-957 (Journal)
Registered Authors
Chen, Zhu
Keywords
expressed sequence tags, full-length cDNA, Human Genome Project, model organism
MeSH Terms
  • Animals
  • Carcinoma, Hepatocellular/genetics
  • China
  • Genetic Techniques
  • Genome, Human*
  • Genomics
  • Hematopoiesis
  • Human Genome Project*
  • Humans
  • Leukemia, Promyelocytic, Acute/genetics
  • Liver Neoplasms/genetics
  • Neurosecretory Systems
  • Transcription, Genetic
  • Tumor Cells, Cultured
PubMed
14744100 Full text @ C. R. Biol.
Abstract
The Chinese genome project was initiated in 1993 with the goal of contributing 1% to the Human Genome Program. The study of gene expression profiles with cDNA microarrays, and large-scale sequencing and analysis of 130928 expressed sequence tags (ESTs), allowed isolation and characterization of over 1000 novel full-length human cDNAs derived from human hematopoietic stem/progenitor cells, neuroendocrine tissues, liver, and cardiovascular cells. In addition, EST sequencing for model organisms, including rat, zebrafish, Schistosoma japonicum and rice was performed, aiming at identifying genes associated with physiological and/or pathological characteristics.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping