ZFIN ID: ZDB-PUB-030117-12
Proneural, prosensory, antiglial: the many faces of neurogenins
Korzh, V. and Strähle, U.
Date: 2002
Source: Trends in neurosciences   25(12): 603-605 (Review)
Registered Authors: Korzh, Vladimir, Strähle, Uwe
Keywords: glia; ngn1; zebrafish; neural plate; delta-notch signaling; gliogenesis; bHLH; xenopus; stem cell; rohon-beard
MeSH Terms:
  • Animals
  • Basic Helix-Loop-Helix Transcription Factors
  • Biological Evolution
  • Cell Differentiation/genetics*
  • Nerve Tissue Proteins/physiology*
  • Neuroglia/physiology
  • Neurons, Afferent/physiology*
  • Xenopus Proteins*
PubMed: 12446121 Full text @ Trends Neurosci.
Previous reports have linked Neurogenin 1 with the general promotion of neurogenesis and gliogenesis. A new study in zebrafish, supported by recent findings in Drosophila, has now challenged this idea by demonstrating that the activity of Neurogenin 1 is limited to activation of development of two classes of sensory neurons.