Gene

mef2d

ID

ZDB-GENE-990415-164

Name

myocyte enhancer factor 2d

Symbol

mef2d Nomenclature History

Previous Names

etID309781.16 (1)
fk53b11
wu:fc50h03
wu:fk53b11
zgc:109833

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Exhibits transcription regulatory region sequence-specific DNA binding activity. Involved in heart formation; positive regulation of transcription by RNA polymerase II; and skeletal muscle myosin thick filament assembly. Predicted to localize to nuclear chromatin. Is expressed in several structures, including adaxial cell; brain; fast muscle myoblast; musculature system; and primitive olfactory epithelium. Orthologous to human MEF2D (myocyte enhancer factor 2D).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 9 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mef2d Human Ortholog

No data available

Associated With mef2d Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002100	Transcription factor, MADS-box
Domain	IPR022102	Holliday junction regulator protein family C-terminal
Domain	IPR033896	MADS MEF2-like
Homologous_superfamily	IPR036879	Transcription factor, MADS-box superfamily

Domain Details Per Protein

Protein	Length	Holliday junction regulator protein family C-terminal	MADS MEF2-like	Transcription factor, MADS-box	Transcription factor, MADS-box superfamily
UniProtKB:Q98870 InterPro	529

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mef2d-201 (1) Ensembl	Havana	3778 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	mef2d-203 (1) Ensembl	Havana	5585 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	mef2d-206 (1) Ensembl	Havana	834 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	mef2d-003 (1) Ensembl	Havana	1610 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	mef2d-004 (1) Ensembl	Havana	543 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab2-mef2	polyclonal	mef2aa mef2ca mef2cb mef2d	IgG	Rabbit	IHC	AnaSpec	5

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations