Gene
hoxb8a
- ID
- ZDB-GENE-990415-108
- Name
- homeobox B8a
- Symbol
- hoxb8a Nomenclature History
- Previous Names
-
- gp-8
- hoxb8
- fj67g02
- wu:fj67g02 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in cell population proliferation and posterior lateral line neuromast primordium migration. Predicted to localize to nucleus. Is expressed in several structures, including nervous system; neural tube; pancreatic system; paraxial mesoderm; and pronephros. Orthologous to human HOXB8 (homeobox B8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64159 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Breau et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000047 | Helix-turn-helix motif |
| Conserved_site | IPR001827 | Homeobox protein, antennapedia type, conserved site |
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeobox domain |
| Domain | IPR020479 | Homeobox domain, metazoa |
| Homologous_superfamily | IPR009057 | Homeobox-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Helix-turn-helix motif | Homeobox, conserved site | Homeobox domain | Homeobox domain, metazoa | Homeobox-like domain superfamily | Homeobox protein, antennapedia type, conserved site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q8AWZ0
|
245 | ||||||
|
UniProtKB:A0A8M2BJC8
|
246 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
hoxb8a-201
(1)
|
Havana | 1817 nt | |
| mRNA | ottdart00000001809 (1) | Havana | 1752 nt |
Interactions and Pathways
No data available
Plasmids